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A significant correlation was seen between lifestyle and both cognitive function and Aβ42/40 ratio.
A threefold improvement was seen in dementia care actions with the 5-Cog paradigm, a culturally adept cognitive detection tool.
Older age, female sex and progression to symptomatic Alzheimer’s disease were associated with driving cessation.
Compared with those without COVID-19, similar deficits were seen for those in whom symptoms resolved in less than four or at least 12 weeks.
Estimated times of divergence of cerebrospinal fluid biomarkers vary from 18 years for Aβ42 to six years for cognitive decline.
Symptoms were linked to increased odds of at least moderate interference with functioning and lower odds of full-time employment.
Harms include increased risks for amyloid-related imaging abnormalities (ARIA)-edema, ARIA-hemorrhage and symptomatic ARIA-edema.
A high false-positive rate was seen when used in primary care with a diverse patient population.
Associations with accelerated cognitive decline and increased dementia risk were seen for white participants and those aged fewer than 65 years.
The CSF 48 panel plus existing biomarkers significantly improved the diagnostic performance for the outcomes studied.