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A reduction was seen in risk for clinically important kidney outcomes and death from cardiovascular causes.
At the prespecified 104-week time point, semaglutide was associated with a lesser decline in eGFR than placebo.
The largest effect sizes were seen for diuretics and calcium channel blockers, and the smallest were seen for ACE inhibitors and beta-blockers.
Octogenarians and nonagenarians can be treated successfully with VEN-HMA.
An initial decrease was seen in proportion with inappropriate prescription, followed by a subsequent increase.
Poorer outcomes were seen for 30-day sustained clinical response and 14-day initial cure rates.
Adjusted odds ratios of 1.70, 1.40 and 1.30 were seen for proton pump inhibitors, H2 receptor antagonists and generic antacids, respectively.
Despite patient beliefs, no effect was seen on the severity or duration of the cough.
ChatGPT deprescribing decisions varied along activities of daily living status, cardiovascular disease history, and medication type
A strong recommendation was given for the addition of an SGLT-2 or GLP-1 agonist to metformin, and lifestyle modifications.