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(HealthDay News) — For patient questions about cancer, artificial intelligence (AI) chatbots can generate quality, empathetic, and readable responses, according to a study published online May 16 in JAMA Oncology.

David Chen, from the Princess Margaret Hospital Cancer Centre in Toronto, and colleagues examined the competency of AI chatbots (GPT-3.5 [chatbot 1], GPT-4 [chatbot 2], and Claude AI [chatbot 3]) to generate high-quality, empathetic and readable responses to questions about cancer. AI chatbot responses were compared to responses from six verified oncologists for 200 patient questions about cancer from a public online forum.

The researchers found that compared with physician responses, responses generated by chatbot 3, which was the best-performing AI chatbot, were consistently rated higher in overall measures of quality, empathy, and readability. There was no significant difference noted between the mean Flesch-Kincaid Grade Level of physician responses and chatbot 3 responses (mean, 10.11 versus 10.31); however, the grade level was lower than that seen for chatbot 1 and chatbot 2 (mean, 12.33 and 11.32).

“Further research is required to investigate the implementation of AI chatbots into clinical workflows with consideration of chatbot scope, data security, and content accuracy in the age of digital health care,” the authors write.

One author disclosed ties to AstraZeneca Canada.

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